American Animals opens in 2003 Kentucky. Barry Keoghan stars as Spencer Reinhard, a disenchanted art student at Transylvania University. His middle-class, suburban life has left him hollow. He yearns for the passion and adventure that inspired the great artists. A chance tour of the school's library leads to a presentation of its rare book collection. The showcase piece, John Audubon's "Birds of America", is the most valuable book in the world.
Evan Peters co-stars as Warren Lipka, Spencer's best friend from high school.