A prophecy predicts that a resourceful man (MacGyver) from the west follows another man (Jack Dalton) to an Ammukash Valley that is supposed to hold the Fountain of Youth. The Valley is, in MacGyver's own words, "Kabulstan, a very hostile third world country that does not like strangers". The prophecy says that the resourceful man has something to do with the destiny of the people of the valley.
MacGyver is not amused to be lured for an 'emergency' to the Himalayan (fictional) Ammukash valley by Jack Dalton, who wants to commercialize the water of 'mir' (spiritual leader) Baba's closed Buddhist pacifist Shangrila society's fountain of youth. Their arrival fits a prophecy of doom, which must refer to the establishment of a covert Chinese nuclear facility run by Dr. Liang with the ruthless help of local renegade guards captain Samad.
- Jack Dalton goes into Kabulstan after hearing stories of natural water source that helps with longevity. MacGyver, tries to get him out, but in the process finds preparations for atomic weapons.