Grey's Anatomy (2005– )
3 user 2 critic

Deterioration of the Fight or Flight Response 

Burke is admitted as a patient, along with Richard's niece. Izzie and the others fight to keep Denny alive, while Alex tries to secure the donor heart for him.


Rob Corn


Shonda Rhimes (created by), Tony Phelan | 1 more credit »


Episode cast overview, first billed only:
Ellen Pompeo ... Dr. Meredith Grey
Sandra Oh ... Dr. Cristina Yang
Katherine Heigl ... Dr. Izzie Stevens
Justin Chambers ... Dr. Alex Karev
T.R. Knight ... Dr. George O'Malley
Chandra Wilson ... Dr. Miranda Bailey
James Pickens Jr. ... Dr. Richard Webber
Kate Walsh ... Dr. Addison Montgomery
Isaiah Washington ... Dr. Preston Burke
Patrick Dempsey ... Dr. Derek Shepherd
Jeffrey Dean Morgan ... Denny Duquette
Loretta Devine ... Adele Webber
Brooke Smith ... Dr. Erica Hahn
Tessa Thompson ... Camille Travis
Hallee Hirsh ... Claire


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Burke is admitted as a patient, along with Richard's niece. Izzie and the others fight to keep Denny alive, while Alex tries to secure the donor heart for him.

Plot Summary | Add Synopsis


Drama | Romance


TV-14 | See all certifications »

Did You Know?


Denny and Adele share a scene in season 1 of Supernatural (2005). See more »


Dr. Isobel "Izzie" Stevens: I cut the L-VAD wire.
Dr. Meredith Grey: Actually, I cut the L-VAD wire.
Dr. George O'Malley: No, I did it. I'm the one who cut the wire.
[pause, Christina remains silent and George gives her a nudge]
Christina Yang: Fine. I cut the L-vad wire.
Dr. Alex Karev: I didn't do anything I'm totally innocent.
[everyone starts yelling at Alex, except Dr. Webber]
Dr. Richard Webber: People! I know who did this so you might as well come clean. I know!
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Look at Her Face
Performed by The Coral Sea
Courtesy of Red Clover Records
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User Reviews

season finale
10 June 2006 | by monkey_936See all my reviews

This episode is by far the best season finale of any show this season. The episode is so tragic and beautiful, everything is absolutely perfect in this episode and although everyone has major roles in this episode the story and drama center around Denny and Izzie. This is one that no one should miss. If you haven't ever watched the show you should because it is the best show on television and this episode proves it. The music adds so much to the show and the official website is awesome because it has a list of all the songs used for every episode. All the main characters are so interesting and real; As a viewer you like them all despite their flaws and personality issues. Anyone who watches a few episodes of this show will love it.

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Release Date:

15 May 2006 (USA) See more »

Company Credits

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Technical Specs


Sound Mix:




Aspect Ratio:

1.78 : 1
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