The story is a prequel to the video game Assassin's Creed II. It centers on Giovanni Auditore, the father of the game's main character, Ezio Auditore da Firenze. Giovanni is an Assassin living in 15th-century Italy during the Renaissance. At this dawn of a new era, a conspiracy is being plotted by one corrupt family to overthrow the powerful Medici family and destroy a unified Italy. As an Assassin, Giovanni must face this threat and bring the guilty parties to justice. The story introduces the situation before Assassin's Creed II, and the enemies of both Giovanni and his son Ezio.