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6 user 35 critic

150 Milligrams (2016)

La fille de Brest (original title)
Dr. Irène Frachon from Brest discovers, that Mediator pills cause heart valve problems/deaths. In 2009, she starts an uphill battle against the producer and the French health authorities.

Director:

Emmanuelle Bercot

Writers:

Irène Frachon (book), Séverine Bosschem (screenplay) | 6 more credits »
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6 nominations. See more awards »

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Cast

Cast overview, first billed only:
Sidse Babett Knudsen ... Irène Frachon
Benoît Magimel ... Antoine Le Bihan
Charlotte Laemmel Charlotte Laemmel ... Patoche
Isabelle de Hertogh Isabelle de Hertogh ... Corinne Zacharria
Lara Neumann Lara Neumann ... Anne Jouan
Patrick Ligardes Patrick Ligardes ... Bruno Frachon
Olivier Pasquier Olivier Pasquier ... Arsène Weber, le Père Noël
Philippe Uchan Philippe Uchan ... Aubert
Gustave Kervern ... Kermarec
Pablo Pauly Pablo Pauly ... Charles-Joseph Oudin
Myriam Azencot Myriam Azencot ... Catherine Haynes
Eddie Chignara Eddie Chignara ... Christophe Laugier
Raphaël Ferret Raphaël Ferret ... Fred, le biostat'
Christophe Meynet Christophe Meynet ... L'assistant de recherches
Gilles Treton Gilles Treton ... Yannick Jobic
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Storyline

Irène Frachon, a doctor who lives in the Breton town of Brest, dares to stand up to the French health and pharmaceutical industry, helping to uncover the media scandal surrounding the commercialization of a controversial medicine whose side effects have caused the death of hundreds of people. Written by jsanchez

Plot Summary | Add Synopsis

Genres:

Biography | Drama

Certificate:

See all certifications »
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Details

Country:

France

Language:

French

Release Date:

23 November 2016 (France) See more »

Also Known As:

150 Miligramas See more »

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Box Office

Budget:

EUR5,600,000 (estimated)

Cumulative Worldwide Gross:

$2,918,159
See more on IMDbPro »

Company Credits

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Technical Specs

Runtime:

Color:

Color

Aspect Ratio:

2.35 : 1
See full technical specs »
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Did You Know?

Trivia

Based on the true story of how a doctor brought to light the harmful effects of a drug which, although intended for use as anti-diabetic medication, was often prescribed "off use" for weight loss and which allegedly resulted in 2,000 or more deaths before being withdrawn from the market through her efforts. See more »

Goofs

A "KEEP CALM AND CARRY ON" variation on the famous meme is seen in the Figaro newsroom in 2010; it's a bit early for French journalists to pick up on that meme, which peaked in 2012-2013. See more »

Connections

References Star Wars: Episode IV - A New Hope (1977) See more »

Soundtracks

Concerto in A minor for four keyboards, BWV 1065: I. Allegro
Written by Johann Sebastian Bach
See more »

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User Reviews

 
Multi-layered whistle blower movie
17 July 2017 | by rubenmSee all my reviews

It is tempting to compare 'La fille de Brest' with 'Erin Brockovich'. Both are about female whistle-blowers, fighting the establishment with all they have. Both are based on actual events. Both are outsiders, initially not taken seriously by their opponents. Both have a star actress in the title role.

But there is an important difference. In 'Erin Brockovich', the title character is much more one-dimensional than in 'La fille de Brest'. Danish actress Sidse Babett Knudsen plays small-town pulmonologist Irène Frachon as an intelligent and passionate woman, who has qualities as well as weaknesses. Her performance really carries the movie.

Doctor Frachon accidentally discovers that some patients suffering from a cardiac disorder also take the drug Mediator against obesity. She suspects that the disorder is a fatal side-effect of Mediator, and embarks on a crusade to prove her point. That's easier said than done, because even with the help of a professor she has a hard time writing a scientifically solid paper. In the sample of patients treated in her hospital, in the small seaside town of Brest, she finds a remarkable correlation between Mediator use and the cardiac disorder. But the drug company and the authorities think the sample is too small to be scientifically acceptable.

The film has not chosen the easy way: the story doesn't simplify things too much. In fact, the start of the movie is not the best part because the viewer feels bombarded by technical information. Later on, the story moves forward more smoothly when Frachon and her team hire a lawyer to represent the patients, find an editor to publish a book about the affair and approach a journalist to write a scoop about it. Also, the involvement of an insider from the health insurance agency gives the story a nice extra dimension.

The film clearly attacks the heavy involvement of the medical industry in the supervision process. According to the end credits, things have changed in France after the Mediator scandal. It would have been a happy end, if several of doctor Frachon's patients wouldn't have lost their lives because of Mediator. Her reading their names aloud during a live television interview, is one of the finest moments in the film. The message is clear: it's all about them, not about reputations, profit or statistics.


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