Family Guy (1999– )
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Lois decides not to vaccinate Stewie to "save" him from autism, causing Stewie to run away, and cause the town to have an outbreak.


Seth MacFarlane (created by), Seth MacFarlane (developed by) | 2 more credits »





Episode cast overview, first billed only:
Seth MacFarlane ... Peter Griffin / Brian Griffin / Stewie Griffin / Dr. Hartman (voice)
Alex Borstein ... Lois Griffin (voice)
Seth Green ... Chris Griffin (voice)
Mila Kunis ... Meg Griffin (voice)
Mike Henry ... (voice)
Chris Cox ... (voice)
Ralph Garman ... (voice)
Jerry Lambert ... (voice)
Rachael MacFarlane ... Miss Tammy (voice)
Hopper Penn ... (voice)
Sean Penn ... Sean Penn (voice)
Danny Smith Danny Smith ... (voice)
Fred Tatasciore ... John Goodman (voice)
Josh Robert Thompson ... (voice)
John Viener ... (voice)


Lois decides not to vaccinate Stewie to "save" him from autism, causing Stewie to run away, and cause the town to have an outbreak.

Plot Summary | Plot Synopsis


Animation | Comedy


TV-14 | See all certifications »




Release Date:

13 November 2016 (USA) See more »

Company Credits

Show more on IMDbPro »

Technical Specs


Sound Mix:




Aspect Ratio:

16:9 HD
See full technical specs »

Did You Know?


Sean Penn voices himself in this episode. His son, Hopper Penn, is also listed in the cast credits. See more »


Peter Griffin: We made this mistake before. We got the other kids vaccinated, but Meg still got chicken pox.
Meg Griffin: Dad, this is acne.
Peter Griffin: Girl, you nasty.
See more »


References The Matrix (1999) See more »

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User Reviews

Worst episode of Family Guy ever made
14 November 2016 | by namikazedanteSee all my reviews

First of all of the staff of family guy should be ashamed to even produce something like this. I actually love Family Guy but this is just... boring plain boring with a agenda about vaccine.

I can't even... I mean how can anyone behind this episode be proud of putting this out to fans and alike? The best joke and yeah best in the sense of how the actually feel and how everybody feels after watching this crap ''Yes it's gonna be a Louise episode'' like Stewie says and pointing out that it's Game of Thrones on another channel.

And yes that is the truth but not just that. This was purely an episode about politics and the use of vaccine. It was actually quite sickening to watch it happen throughout the episode. My Respect for Seth McFarlane dropped very low. That he could stand behind this kind of excuse for a comedy show? I mean what the hell?

This episode was just boring and I want to forget I ever seen it. Wait that just happened now because there is nothing that is memorable about it. It's first We need to stop vaccine then throughout the second half. Oh wait ! I learned my lesson... the end. And that's the episode. So yeah I kinda was looking forward to this weeks episode . Thanks for the false hope :)

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